Protect - While any time of day is a good time to provide a jolt to your mitochondria,, best-practice is to take in the morning to kick off your day or before a night on the town prior to drinking alcohol. Soothe - Any time of day is a good time to get some additional Omega-3's into your diet and supplement routine. Restore - While any time of day is a good time to add some powerful adaptogens into your diet and supplement routine, best-practice is to take in the evening to relax and unwind after a busy day.